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Dilemmas when sex development goes awry. The fetus is influenced by its Gril in gril adult and what it is exposed to. For example, babies that have a low birth weight and grow slowly are more likely to have heart disease or type 2 diabetes as adults.

The impacts of what the baby experiences while in the womb on their health as adults is known as the Barker hypothesis. A well-known example of this is Canoas the slut Dutch famine of This resulted in five to six months of calorie restriction for the affected population.

Studies show mothers who faced Gril in gril adult restriction early in pregnancy the first 13 weeks had a child who was more likely to suffer from heart disease as an adult.

The children of those who were in the later stages of pregnancy during the famine the last 13 weeks of pregnancy were more Gril in gril adult to develop type 2 diabetes in adulthood. Smoking during pregnancy is more likely to result in the birth of a small baby. It is also associated with behavioural problems in Gril in gril adult adukt adolescence, as well as adverse health outcomes such as birth defects, asthma and allergies.

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But the impacts of these exposures during pregnancy, as well as their severity, depend on the sex of the baby. It found adult men whose mothers smoked during pregnancy had worse problem-solving skills and vocabulary than men not Gril in gril adult to maternal smoking.

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But no negative effects were seen in the Single Gippsland girl children of mothers who smoked. Too much exposure to heavy metals — such as cadmium — during pregnancy is associated with adverse health effects in children including cancer, diabetes and heart disease.

Pregnant women can be exposed to heavy metals through work and manufacturing processes, as well as smoking and diet. Many other studies show how different sexes may inn differently to adverse exposures during pregnancy.

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These studies are difficult to explore in humans due to the number and range of adverse exposures one accumulates after birth. So they only offer associations between the two events, rather than evidence one caused the other.

For instance, studies of genetically identical twins show, as Gril in gril adult, one twin may develop type 2 diabetes or heart disease while the other twin remains healthy. Although the twins shared an identical environment in the womb, their different environments after birth meant they were exposed to different things as they aged.

Sex differences in response to adverse exposures during pregnancy may be mediated by the placenta. It also takes care of waste, gases and hormone production.

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The placenta actually has the same DNA sequence as the baby, not Gril in gril adult mother. Boys grow faster than girls during gestation and are on average grams heavier than girls at birth. This is because they are more likely to extract maximum nutrients from their placentas.

But this also means boys leave little in reserve and are are more likely to be undernourished or stillborn if something goes wrong in pregnancy. However, girls slow their growth when exposed to adversity during pregnancy in order to survive.

Why males are more likely to die from conception to old age. A possible reason for these sex differences may hark back to our evolutionary past when relatively few males survived to adulthood and reproduced.

Those who did tended to be the biggest and strongest and most able to compete to pass Gril in gril adult their genes to the Grril generation.

We are not Gril in gril adult sure why boys and girls respond differently to adverse exposures during pregnancy. And while sex chromosomes play a large role, they may not be wholly responsible.

We assessed gene adutl in placentas from uncomplicated pregnancies and found genes that were different between boys and girls.

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ggil Gril in gril adult than half of these genes were not on the sex chromosomes. A lot more research is needed to try to understand why boys and girls grow differently during pregnancy and why they respond differently to adverse exposures during pregnancy.

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